ICL -> MUS81 PCNATLS -| ADD XPF -> ADD FAN1 -> ADD MUS81 -> ADD ADD -> ADD FANCJBRCA1 -| NHEJ ssDNARPA -> NHEJ DSB -> NHEJ XPF -> NHEJ KU -> NHEJ DNAPK -> NHEJ ATR -> NHEJ ATM -| NHEJ CHKREC -| NHEJ DSB -> ATM ATR -> ATM CHKREC -| ATM FAcore -| XPF FAN1 -> XPF FANCD2I -> XPF p53 -> XPF MUS81 -> XPF FANCM -| XPF ICL -> FANCM CHKREC -| FANCM FANCM -> FAcore ATR -> FAcore CHKREC -| FAcore ATM -> FAcore ssDNARPA -> RAD51 FANCD1N -> RAD51 CHKREC -| RAD51 ICL -> ICL DSB -| ICL DSB -> H2AX DNAPK -> H2AX ATR -> H2AX ATM -> H2AX CHKREC -| H2AX DSB -> DNAPK KU -> DNAPK CHKREC -| DNAPK CHK1 -> p53 DNAPK -> p53 CHK2 -> p53 ATR -> p53 CHKREC -| p53 ATM -> p53 PCNATLS -> CHKREC ICL -| CHKREC DSB -| CHKREC ADD -| CHKREC HRR -> CHKREC CHKREC -| CHKREC NHEJ -> CHKREC USP1 -| PCNATLS FAcore -> PCNATLS FAN1 -| PCNATLS ADD -> PCNATLS DSB -> DSB XPF -> DSB FAN1 -> DSB HRR -| DSB NHEJ -| DSB FANCJBRCA1 -> ssDNARPA DSB -> ssDNARPA MRN -> ssDNARPA FANCD2I -> ssDNARPA KU -| ssDNARPA RAD51 -| ssDNARPA H2AX -> FANCD2I USP1 -| FANCD2I FAcore -> FANCD2I DSB -> FANCD2I ATR -> FANCD2I ATM -> FANCD2I DSB -> HRR FANCD1N -> HRR BRCA1 -> HRR RAD51 -> HRR CHKREC -| HRR ssDNARPA -> FANCD1N FANCD2I -> FANCD1N BRCA1 -> FANCD1N CHKREC -| FANCD1N ssDNARPA -> ATR FANCM -> ATR CHKREC -| ATR ATM -> ATR DSB -> MRN KU -| MRN FANCD2I -> MRN CHKREC -| MRN RAD51 -| MRN ATM -> MRN DNAPK -> CHK1 ATR -> CHK1 ATM -> CHK1 CHKREC -| CHK1 FANCD2I -> FAN1 MUS81 -> FAN1 DSB -> BRCA1 CHK2 -> BRCA1 ATR -> BRCA1 ATM -> BRCA1 CHKREC -| BRCA1 ssDNARPA -> FANCJBRCA1 ICL -> FANCJBRCA1 ATR -> FANCJBRCA1 ATM -> FANCJBRCA1 DSB -> KU FANCD2I -| KU MRN -| KU CHKREC -| KU DNAPK -> CHK2 ATR -> CHK2 CHKREC -| CHK2 ATM -> CHK2 PCNATLS -> USP1 FANCD2I -> USP1 FANCM -| USP1 FANCD1N -> USP1 $ADD: ((ADD & !PCNATLS) | ((MUS81 & (XPF | FAN1)) & !PCNATLS)) $ATM: ((DSB & !CHKREC) | (ATR & !CHKREC)) $ATR: (((ATM & !CHKREC) | (FANCM & !CHKREC)) | (ssDNARPA & !CHKREC)) $BRCA1: ((DSB & ((CHK2 | ATR) | ATM)) & !CHKREC) $CHK1: (((DNAPK & !CHKREC) | (ATR & !CHKREC)) | (ATM & !CHKREC)) $CHK2: (((ATM & !CHKREC) | (DNAPK & !CHKREC)) | (ATR & !CHKREC)) $CHKREC: ((((PCNATLS & !DSB) | (NHEJ & !DSB)) | (HRR & !DSB)) | !((((((PCNATLS | ICL) | DSB) | ADD) | HRR) | CHKREC) | NHEJ)) $DNAPK: ((DSB & KU) & !CHKREC) $DSB: (((DSB & !(HRR | NHEJ)) | (XPF & !(HRR | NHEJ))) | (FAN1 & !(HRR | NHEJ))) $FAN1: (MUS81 & FANCD2I) $FANCD1N: ((ssDNARPA & BRCA1) | ((FANCD2I & ssDNARPA) & !CHKREC)) $FANCD2I: ((FAcore & ((ATR | ATM) | (H2AX & DSB))) & !USP1) $FANCJBRCA1: ((ssDNARPA & (ATR | ATM)) | (ICL & (ATR | ATM))) $FANCM: (ICL & !CHKREC) $FAcore: ((FANCM & (ATR | ATM)) & !CHKREC) $H2AX: ((DSB & ((DNAPK | ATR) | ATM)) & !CHKREC) $HRR: ((DSB & ((FANCD1N & BRCA1) & RAD51)) & !CHKREC) $ICL: (ICL & !DSB) $KU: (DSB & !((FANCD2I | MRN) | CHKREC)) $MRN: ((DSB & ATM) & !((CHKREC | (KU & FANCD2I)) | RAD51)) $MUS81: ICL $NHEJ: (((XPF & (DSB & DNAPK)) & !((FANCJBRCA1 & ssDNARPA) | CHKREC)) | ((KU & (DSB & DNAPK)) & !(ATM & ATR))) $PCNATLS: (((FAcore & ADD) & !(USP1 | FAN1)) | (ADD & !(USP1 | FAN1))) $RAD51: ((ssDNARPA & FANCD1N) & !CHKREC) $USP1: ((PCNATLS & !FANCM) | ((FANCD1N & FANCD2I) & !FANCM)) $XPF: (((p53 & MUS81) & !(FAcore & (FAN1 & FANCD2I))) | (MUS81 & !FANCM)) $p53: ((((ATR & CHK1) & !CHKREC) | ((ATM & CHK2) & !CHKREC)) | (DNAPK & !CHKREC)) $ssDNARPA: ((DSB & (MRN | (FANCJBRCA1 & FANCD2I))) & !(RAD51 | KU))